AGTR1 and hypertensive disorder: To identify potential downstream molecular events that may be responsible for the effects of renin-a deletion in hypertension maintenance, we examined the impact of renin-a ablation in the SFO on Ang II type 1a (AT1aR) and type 2 (AT2R) receptors 7 and 14 days after DOCA-salt treatment (Figure 9A).