Since 2007, many new antibodies targeting neuronal surface antigens and synaptic proteins causing new forms of autoimmune encephalitis have been discovered, including those caused by autoantibodies targeting GABAB-R, GABAA-R, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), and contactin-associated protein-like 2 (CASPR2), and the list continues to grow (Figure 3). This evidence concerns the gene CNTNAP2 and autoimmune encephalitis.