Gaucher disease (GD) is an autosomal recessive genetic disease whose incidence varies between 0.4 and 5.8/100,000 inhabitants; GD can be attributed to a deficiency of the lysosomal enzyme, glucocerebrosidase, which leads to the accumulation of its substrate (glucosylceramide) in lysosomal macrophages [77]. This evidence concerns the gene GBA1 and Gaucher disease.