Lastly, the expression of lung cancer-related genes including Ddr2, Fgfr1, Her2, Met, Stk11, and Egfr was also significantly upregulated in the imPAC2-KRAS/TP53R273H group, compared with that of the imPAC2 control group (Fig. 7C-c). Here, EGFR is linked to lung cancer.