In completed phase 1/2 study of DSP-7888 in patients with higher-risk myelodysplastic syndrome (MDS) who had failed prior azacytidine treatment, intradermal DSP-7888 Emulsion treatment was well tolerated and a total of 78.7% of patients experienced a positive WT1-specific immune reaction (IR) defined as delayed type hypersensitivity reaction-positive or WT1-specific CD8+ T cell positivity [27]. This evidence concerns the gene CD8A and myelodysplastic syndrome.