Regarding this last point, we discovered that the WT1-specific CD8+ T cells induced by nelatimotide-only Emulsion (i.e., DSP-7888 Emulsion without adegramotide) did not become activated when co-cultured with tumor cells, including when treated with anti-PD-1, but DSP-7888 Emulsion-induced CD8+ T cells did. The gene discussed is PDCD1; the disease is neoplasm.