Park et al.95 isolated highly purified exosomes from malignant pleural effusion of NSCLC patients and identified potential diagnostic markers, including EGFR, K-Ras, basigin, carcinoembryonic antigen-related cell adhesion molecule 6, claudin1, claudin3, and RAB family proteins. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.