IL6 is a pro-inflammatory cytokine upregulated in a number of cancers, including breast [47], prostate [48], endometrial [49], renal cell carcinoma [50], oral squamous cell carcinoma [51], multiple myeloma [52], colorectal cancer [53] and pancreatic cancer [54]. The gene discussed is IL6; the disease is hereditary clear cell renal cell carcinoma.