However, these chimeric mice were more susceptible than Epha2–/– mice reconstituted with Epha2–/– BM (KO→KO), which recapitulated the phenotype observed in global Epha2–/– mice (Fig. 1b), suggesting that EphA2 deficiency within cells of both, the hematopoietic and stromal compartments, is required for full protection against disseminated candidiasis. The gene discussed is EPHA2; the disease is disseminated candidiasis.