Comparison of HER2 mRNA (EdgeSeq) and protein levels by H-score (Supporting Information [S4A Fig in S8 File] and Supporting Information) in the TMA data set defined simple correlations whereas differences in median HER3 EdgeSeq mRNA and protein (IHC H-score) levels varied by cancer type/subtype (Fig 3B). The gene discussed is ERBB2; the disease is cancer.