The results of the multivariate analysis evaluating predictors of treatment failure in the IV to oral transition group are shown in Table 4; Independent predictors of treatment failure included metastatic solid cancer (aOR = 4.355, 95% CI 1.727–10.979), HIV infection with a CD4 count < 200 cells/mm3 (aOR = 8.452, 95% CI 1.150–62.114), qSOFA score of ≥ 2 (aOR = 2.545, 95% CI 1.145–5.658), multidrug-resistant pathogen (aOR = 2.849, 95% CI 1.213–6.693), and respiratory tract infection (aOR = 8.447, 95% CI 3.195–22.331). Here, CD4 is linked to Respiratory tract infection.