KRAS and non-small cell lung carcinoma: In NSCLC adenocarcinoma, KRAS G12C, G12V, and G12D are the most common KRAS alterations observed, seen in 40.5%, 19.8%, and 14.7% of KRAS mutated adenocarcinoma, respectively [56], where these 3 variants account for over 75% of cases.