ZFYVE9 and systemic sclerosis: We generated mice that overexpress SARA specifically in PDGFR-β+ cells (PDGFRb-CreSARATg mice, SARATg hereafter) (40) (Supplemental Figure 1; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.160977DS1), then subjected them and their WT littermates (PDGFRb-CreSARA–/– mice, SARAWT hereafter) to repeated subcutaneous injections of bleomycin, a widely used method to model SSc in mice (41–43).