In C/G-CB (>9 weeks in EC coculture), WSU-AML, and Kasumi-1 FOLR1+ xenograft models, treatment with FOLR1 CAR T cells resulted in leukemia clearance, while disease progression occurred in all mice that received unmodified T cells (Figure 6D and Supplemental Figure 12, A and B). This evidence concerns the gene FOLR1 and leukemia.