IGHG3 and COVID-19: We examined whether response rates of SARS-CoV-2–specific antibodies (IgG1, IgG3, total IgG, and IgA) differed between PLWH and PWOH participants after adjusting for peak COVID-19 symptom severity, demographics, preexisting medical conditions, smoking history, region, and days since SARS-CoV-2 diagnosis.