Participants with a higher cardiometabolic risk score were likely to be older, have lower levels of physical activity, be with higher levels of BMI, WC, SBP, DBP, FPG, TG, and INS and have a higher prevalence of T2DM, hypertension, and dyslipidemia (all p < 0.05). The gene discussed is INS; the disease is type 2 diabetes mellitus.