In vitro studies of granule neurons from the cerebellums of mice showed that MeHg exposure impaired cofilin phosphorylation balance [66], while the study of Shao et al. [67] compared the different response patterns of astrocytes and cerebellar granule neurons upon MeHg exposure and showed the regulation of the cytoskeleton, mitochondria components, and even Huntington’s disease features based on KEGG pathway enrichment analysis. The gene discussed is CFL1; the disease is juvenile Huntington disease.