Thus, these proteins may be considered as potential predictors or biomarkers for neurological outcomes associated with mercurial exposure, mainly because the malfunctioning of both the HSP and UPS systems can lead to protein aggregation, which characterizes various neurodegenerative diseases, such as Alzheimer’s (AD), Parkinson’s, and Huntington’s diseases [44]. Here, HSP90B2P is linked to neurodegenerative disease.