In summary, current studies have shown that the occurrence of arrhythmias in patients with COVID-19 may be attributed to changes in angiotensin converting enzyme 2 expression, myocarditis, cytokine storm, hypoxemia, myocardial strain, electrolyte abnormalities, intravascular volume imbalance, drug interaction and stress response caused by viral infection (Figure 1). The gene discussed is ACE2; the disease is Arrhythmia.