In addition, the level of inflammatory cytokines in the plasma of patients in ICU and arrhythmia incidence were higher than that of patients not in ICU [19,50,59], inflammatory cytokines, such as IL-6 and IL-8, are associated with lung injury and poor prognosis in patients with COVID-19, and IL-6 and IL-10 are significantly elevated in patients with severe COVID-19 pneumonia, suggesting that the inflammatory response was related to the severity of infection and impacts arrhythmias occurrence [55]. This evidence concerns the gene CXCL8 and Arrhythmia.