APP and Sepsis: Specifically, animals that were subjected to abdominal sepsis were slower in their exploration (2.24 ± 0.38 cm/min for WT-Sepsis, 2.87 ± 0.87 cm/min for EarlySepsis and 3.2 ± 1.63 cm/min for LateSepsis) (p < 0.0001) (Figure 3e) compared with animals that were not subjected to sepsis (7.27 ± 1.11 cm/min in APP Sham animals).