Meanwhile, we found that high expression of lncRNAs (AP003119.3, RNF216P1, AC156455.1, AL360270.1, AP003555.1, AL513550.1) was associated with increased risk in COAD patients, indicating that these lncRNAs are high-risk lncRNAs. This evidence concerns the gene RNF216P1 and colon adenocarcinoma.