PHF5A and colorectal carcinoma: In addition, Cao et al. analyzed the HCT116 and SW480 cells infected by ETBF; they identified that downregulated miR-149-3p may facilitate Th 17 cell differentiation and target PHF5A to promote CRC cells proliferation, suggesting the measurement of miR-149-3p in plasma exosomes could be an effective approach to predict active UC and UC-CRC [114].