Somatic mutations in oncogene-encoding genes, such as epidermal growth factor receptor (EGFR), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), Kirsten rat sarcoma viral oncogene homolog (KRAS), and Akt serine/threonine kinase 1 (AKT1), are more diverse in NPC than in other cancers [7]. This evidence concerns the gene PIK3CA and cancer.