Additionally, we extracted the insulin response of the right putamen in 34 age-matched participants from a cross-sectional study (13), specifically in 17 participants of healthy weight (7 women, 10 men; mean age 26.8 ± 2.8 years; mean BMI 22.8 ± 1.4 kg/m2) and 17 participants of overweight and obesity (8 women, 9 men; mean age 26.4 ± 2.3 years; mean BMI 30.4 ± 3.9 kg/m2). Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.