RYR3 and chronic kidney disease: RYR3 rs877087 TT homozygotes (461 CKD cases in 6164 TT homozygotes) were more likely to have hospital‐diagnosed CKD compared to the common homozygotes groups (HR 1.18, 95% CI 1.04 to 1.34, P = .01; see Table S8 for details).