We expanded the initial analysis by examining the SIRT6 genotype in a total of 569 individuals with FRDA; 89% of patients (n = 511) were homozygous at the SIRT6 SNP locus with thymine on both alleles (from here on, this group is known as “TT”), and 10% of individuals (n = 56) were heterozygous at the SIRT6 SNP locus with cytosine on allele 1, and thiamine on allele 2 (from here on, this group is known as “CT”). This evidence concerns the gene SIRT6 and Friedreich ataxia.