The survival analysis for the HCC patients with hepatitis risk factor were performed and the results showed that patients with higher expression of ESR1, MAPK8, HNF4A, BCL2L1, PTEN, and EGFR had a better 5-year overall survival (Figures 6A–F), while those with lower expression of HDAC1 genes had a better prognosis (Figure 6L). The gene discussed is ESR1; the disease is hepatocellular carcinoma.