MAPK4 and Miyoshi myopathy: In contrast, circ_0000190 was downregulated in both peripheral blood and bone marrow tissue; further in-depth mechanistic experiments explored that circ_0000190 repressed miR-767-5p, subsequently targeting and regulating mitogen-activated protein kinase 4 (MAPK4), which contributed to inhibiting MM progression (Feng et al., 2019).