GPT and obesity due to melanocortin 4 receptor deficiency: It is worth mentioning in this context, that children with overweight/obesity and elevated ALT values had a more than 2-fold increased risk for future dysglycemia independent of age, sex and BMI-SDS in a survival analysis of up to 11 years of follow-up of 510 children with overweight and obesity from the Leipzig Childhood Cohort.