ERBB2 and cancer: The positively charged antibodies, including anti-HER2 (anti-C-erbB-2-HER2/NEU) and anti-CEA8 (anti-CEA8 cam8/CD67), were adsorbed onto the surface of the negatively charged core–shell nanoparticles for further application for early cancer diagnosis.152 Kobayashi et al.153 modified the surface of positively charged Au@SiO2@NH2 by simply adding cellulose, and the final product was used in X-ray imaging and Kong and co-workers described the hydrogen bonding of europium and terbium coordination polymers based on o- and p-phthalic acid chelate on the surface of Ag@SiO2 core–shell nanoparticles.