For example, it has been observed that mutant Epidermal Growth Factor Receptor (EGFR) protein can be transferred to neighboring cells via cancer cell derived EVs and promote a tumorigenic phenotype in recipient cells.6 Additionally, EVs released by glioblastoma cells deliver protein and RNA cargoes to recipient cells to promote angiogenesis and tumorigenesis.12 Cancer cell EVs support not only local cell-to-cell communication, but also act on cells at distant sites. The gene discussed is EGFR; the disease is glioblastoma.