Very recently, Tang and co-workers developed a TphDha-COF-based theranostic nanoplatform (Fig. 73A) by integrating tetramethylrhodamine-labeled survivin antisense strand onto TphDha COF for simultaneous cancer diagnosis and PDT.405 The fluorophore was quenched by TphDha COF due to its large plane π-electron system. This evidence concerns the gene BIRC5 and cancer.