Anemia in adults with CKD is defined as Hb < 13 g/dL in men and < 12 g/dL in womenGuidelines provide specific recommendations on iron supplementation and ESAs in this populationGoal should be to maintain Hb level between 10-12 g/dL as many studies have consistently shown better outcomes in HD, PD, and pre-dialysis patients, without an increase in adverse reactions. This evidence concerns the gene GSTM1 and anemia (phenotype).