In this study, although the difference was not statistically significant, cases with high CD8-positive iTILs and low FOXP3-positive iTILs showed a tendency to recur, it is possible that CD8-positive iTILs are classified into positive and negative subtypes for tumor immune function, which can be clarified by prospective analysis using mIHC together with additional markers. Here, CD8A is linked to neoplasm.