However, low PNI was related not only to GGT (> 50 U/L) (P = 0.007), but also to PLT (< 100 × 10^9/L), ALB (< 35 g/L), TBIL (> 17.1 μmol/L), ALT ( > 40 U/L), AST (> 40 U/L), Cirrhosis, portal hypertension and Child-Pugh B (all p < 0.05). The gene discussed is ALB; the disease is portal hypertension.