ABCB10 and breast cancer: Furthermore, gain and loss assays showed that Circ-ABCB10 and DUSP7 knockdown could actively increase the susceptibility of BC cells to paclitaxel by activating let-7a, and overexpression of these important molecules could increase PTX sensitivity, apoptosis, and have an inhibitory impact on the invasion and autophagy of PTX-resistant BC cells (53).