- Quality of life patient-reported outcomes: QLQ30 and PR25- Physician-reported CTCAE Genitourinary (GU) and Gastrointestinal (GI) late toxicity- PSA (Prostate Specific Antigen) biochemical failure- Distant metastatic failure- Overall and prostate cancer specific survival. The gene discussed is KLK3; the disease is prostate carcinoma.