Nonetheless, despite their strong correlations and concordant upregulation with NACT, it is important to note their potential differing functions, even among the two top upregulated transcription factors, ATF3 and EGR1. As a point of comparison, we observed the relationship of gene expression levels of these two transcription factors with patient PFS using Gene Expression Omnibus (GEO) Series (GSE) and TCGA ovarian cancer data in the KMplotter (28). This evidence concerns the gene ATF3 and ovarian carcinoma.