We further identified the relationship between the 19 selected genes and BC and T2DM in DisGeNET and MalaCards, and we obtained relevant information for each gene, except ERGIC2 and DDX52. Although ERGIC2 and DDX52 play important roles in the TF-miRNA‒mRNA network and mRNA-RBP-pseudogene network, the functions of ERGIC2 and DDX52 in BC and T2DM need further research. The gene discussed is TF; the disease is breast cancer.