This metabolic reprogramming is more readily observed in tumor-infiltrating MDSCs, and features increased CD36-mediated FA uptake and higher expression of key enzymes (e.g., CPT1a, medium-chain acyl-CoA dehydrogenase (ACADM), peroxisome proliferator-activated receptor gamma co-activator 1-β (PGC1-β), and 3-hydroxyacyl-CoA dehydrogenase (HADHA)). The gene discussed is CPT1A; the disease is neoplasm.