In addition, an analysis of the correlation between the OS and DFS of patients with BC and hub genes showed that patients with BC showing altered expression of ACTA2, COL3A1, TPM1, ACTC1, and ACTN1 exhibited a worse OS, while those with altered expression of PPARG had a better OS, and only high-expressed ACTC1 could predict a worse DFS (Fig. 6B). The gene discussed is COL3A1; the disease is breast cancer.