As a sponge for miR-495, UCA1 binds and inhibits miR-495, promotes the expression of hepatocyte growth factor (HGF) and c-MET, activates the HGF/c-MET signaling pathway in CRC cells, and attenuates the Cetuximab-induced cell proliferation inhibition, thereby promoting Cetuximab resistance [32]. The gene discussed is HGF; the disease is colorectal carcinoma.