IL1B and heart failure: Recently, the CANTOS trial, which targeted IL-1β with the monoclonal antibody, contributed to improved heart failure outcomes in myocardial infarction patients, raises the renewed interest in inflammation of heart failure (Shetelig et al. 2018; Dong et al. 2012; Damås et al. 2000a; Frangogiannis 2014) Chemokine is a family of inflammatory cytokines which are able to cause directional migration and activation of immune cells (Caidahl et al. 2019; Noels et al. 2019; Frangogiannis and Entman 2004; Liehn et al. 2011).