In Crohn’s disease, levels of ENTPD1 and IL10 were higher in Th17 cells exposed to UCB and FANA-PGK1 or FANA-ALDOA than in those exposed to UCB alone; this increase was significant in the case of IL10 and trended towards significance for ENTPD1 (Fig. 5a, c). Here, IL10 is linked to Crohn disease.