Depression showed an overlap with sedentary behaviour in the gene MEF2C (Zdep = 4.53, pdep = 2.95 × 10–6; Zsb = 4.43, psb = 4.77 × 10–6, with relative amplitude in CCDC36 (Zdep = 4.30, pdep = 8.66 × 10–6; Zra = 4.41, pra = 5.28 × 10–6), and with daytime sleepiness in ERBB4 (Zdep = 6.97, pdep = 1.63 × 10–12; Zds = 4.39, pds = 5.80 × 10–6). Here, MEF2C is linked to major depressive disorder.