GPT and metabolic syndrome: In the cardiometabolic risk assessment based on our novel references, components of MetS significantly increased in high levels of AST, ALT, and AST/ALT ratio; some of the components were increased even in borderline high levels of liver enzymes in the analysis of ANCOVA with correction of age, sex, BMI, etc. Similarly, the odds ratio of metabolic risk factors also increased in the high AST, ALT, and the low AST/ALT ratio; some components of MetS were significantly increased even in borderline high levels.