To mimic pathological changes in schizophrenia patients, we generated a DISC1exon3 flox mouse strain, and crossed it with the OPC-specific NG2CreERT mice to obtain NG2CreERT:DISC1exon3 fl/+ (DISC1-Δ3) mice (Supplementary Fig. 2d). The gene discussed is DISC1; the disease is schizophrenia.