SNHG1 and neuroblastoma: Functional assays were used to further validate the effect of the depletion of SNHG1 expression, and showed induced cell differentiation (Fig. 2D, E), G1-phase cell cycle arrest (Fig. 2F), apoptosis (Fig. 2G), and ROS accumulation (Fig. 2H), as well as suppression of cell migration in NB cells (Fig. 2I).