Second, stratifying the 54 TCGA GBM with reverse phase protein array (RPPA) data by their level of EGFR activation, as measured by phosphorylation of EGFR Y1068 (Rojas et al., 1996), shows that a high level of EGFR activation is associated with greater TERT expression (Figure 2A). The gene discussed is EGFR; the disease is glioblastoma.