Upregulation of genes associated with other diseases, renal dysfunction or cancer was also observed, such as Fras1 (Fraser syndrome 1), Cyp21a1 (congenital adrenal hyperplasia), Dbh (associated with kidney dysfunction), and Akr1c1/Myt1/Myf6/Scg2 (kidney cancer) (Figure 1B). This evidence concerns the gene FRAS1 and cancer.