In association with RNA-seq results, intestinal development-related genes, such as Arg2, Treh, Lyz1, Gip, Lct, Kcnj13, and Slc2a2, were significantly increased in the intestine of mice administered CFS from DS0384 (Figure 6(g). Here, ARG2 is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.