LEP and Insulin resistance: Serum leptin showed highly significant negative correlation with Homeostatic Model Assessment for Insulin Resistance (HOMAIR) (r = -0.316) (p-0.006), whereas C peptide showed high significant negative correlation with total cholesterol (r = -0.394), LDL(r = -0.372) and positive significant correlation with HOMAIR (r = 0.283) (Table 5) with p values being 0.001, 0.001, and 0.015 respectively (Table 4).